Current Issue : July - September Volume : 2014 Issue Number : 3 Articles : 5 Articles
The world health organization has described obesity as one of today�s most neglected public health problems,\r\naffecting every region of the globe. The present study was planned to evaluate antiobesity activity of Hippophae rhamnoides L.\r\nseeds in MSG induced-obese mice. Hydro alcoholic extract of Hippophae rhamnoides L. seeds (HEHS) (286 and 667 mg.kg-1.d-1)\r\nor vehicle control treatment was given orally once a day for 56 days to MSG induced-obese mice. Food intake, water intake,\r\ngrowth curve, body weight, total body fat and other biochemical parameter evaluated. Lipid profile and glucose were quantified\r\nat the start (t = 0), 14, 28, 42 and 56 days after the administration of the extract whereas plasma insulin, adiponectin and leptin\r\nwere assessed at the end of the experimental protocol. After 56 days HEHS treatment, it could effectively lower the body weight\r\nand total body fat content and significantly flattened (P<0.05) adiposity index of MSG-induced obese mice as compared with\r\nuntreated MSG-induced obese mice. HEHS also the significantly decreased plasma levels of triglyceride, total cholesterol, leptin\r\nand insulin whereas increased adeponectin level as compare to MSG control group. In conclusion, HEHS showed a potential antiobesity\r\neffect in MSG-induced mice, which may be mediated by altering plasma peripheral peptides level particularly leptin,\r\ninsulin and adeponectin with body fat distribution. Even though, more studies are needed to support this promising mechanism\r\nand chemical constitute responsible for its anti-obesity effect....
Myocardial infarction is resulted from imbalance between the coronary oxygen supply and demand to myocardium of\r\nheart. Ischemic heart diseases are leading causes of mortality in developed and developing countries. It is well recognised that\r\nformation of reactive oxygen species such as superoxide anion and hydroxyl radical and other species in the ischemic zone can\r\ndamage the cell membrane lipids, proteins, carbohydrates and DNA and result in cell dysfunction and apoptosis. Traditionally\r\nclove is used as culminate in diet obtained from clover bud of Eugenia caryophyllus. Clove oil contain eugenol, is a good\r\nantioxidant. The present study was aimed to study the effect of clove oil on serum marker enzymes, lipid peroxidation and\r\nendogenous antioxidants in isoproterenol (ISO)-induced myocardial infarction in rats. Adult male albino rats, treated with ISO\r\n(100 mg/kg, S.C) for 2 days at an interval of 24 h caused a significant (P<0.001) elevation of serum marker enzymes, lipid\r\nperoxidation and whereas there was a significant (P<0.001) decrease in endogenous antioxidants. Administration of clove oil\r\n(719.5/kg/oral) for 15 days and challenged with ISO on the day 14th and 15th showed a significant (P<0.001) decrease in serum\r\nmarker enzymes, lipid peroxidation and a significant (P<0.001) increase in the endogenous antioxidants. These findings indicate\r\nthat clove oil has cardio protective effect against ISO induced myocardial infarction in rats....
Traditional medicine systems are part of India’s culture. Today the whole world has become increasingly interested in Indian ayurveda and other traditional health care systems. Barleria is an important medicinal plant which is commonly known as vajradanti and used by tribal people for the treatment of toothache, cough, fever, anemia, rheumatism, piles and as an antidote for snake-bites. This plant is also used in ayurveda, siddha, allopathy and folklore systems of medicines. We found three species of Barleria viz. Barleria prionitis Linn, B. strigosa willd and B. cristeta Linn growing wildly in takhaji, hinglaj garh and gandhi sagar wild life sanctuary of mandsaur district of madhya pradesh. A variety with white flowered was found only in takhaji growing wildly. It was reported by prain and cooke as a verity of B. cristeta var. dichotoma. This verity was not reported earlier as growing wildly. We reported all varieties of Barleria first time in mandsaur district in wild condition. Barleria prionitis Linn and B. strigosa willd was included in the list of threatened medicinal plants....
This study was designed to ascertain the antioxidant and in-vivo antihyperglycemic property of leaves extracts of Wendlandia thyrsoidea (R. and S.) Steud. in streptozotocin-nicotinamide induced type 2 diabetic in rats model. 2,2-diphenyl-1- picrylhydrazyl (DPPH) radical scavenging capacity, reducing power, total antioxidant capacity, scavenging of H2O2 and metal chelating ability for ferrous ions were used to screen the antioxidant properties of extracts. Streptozotocin-nicotinamide induced type 2 diabetic in rats model was used to screen antihyperglycemic property. The extracts showed significant antioxidant activity in correlation to extracts phytoconstituents. The IC50 value for antioxidant property of aqueous extract of leaves was found to be 49.33±1.79 µg/ml by DPPH radical scavenging, 77.53±2.07 µg/ml by Fe2+ chelating activity and 100.70±1.31 µg/ml for scavenge H2O2. The significant decreasing blood glucose level and increasing in body weight on treatment with extracts on streptozotocin-nicotinamide induced type 2 diabetic rats implies the anti-hyperglycemic activity of leaves. The obtained results showed the plant have potential antioxidant and antihyperglycemic property and suggesting further study to isolate the compound responsible for the biological activity....
The use of medicinal plants is gaining momentum from the last few decades. Though the knowledge of using medicinal plants dates back, the advances in chemical and pharmaceutical investigations added a great level of status to the use of these plants by revealing the presence of active principles and their actions on human and animal systems. One such garden vegetable plant showing a wide range of applications is raphnus, a genus from the family of brassicaceae. Raphnus well known as “mullangi” is an annual or biennial herb with succulent taproot which has been used as food sine prehistoric time. All the parts of the plant have medicinal values and are used in treating various ailments. The present review mainly focus on the pharmacological, phyto chemical, ethno botanical, pharmacological uses of mullangi....
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